Research progress on mechanism of Zhizi(Gardeniae Fructus)in treating liver diseases
Liver diseases are widespread and seriously threaten the life and health of the Chinese people.Currently,the treatment of liver diseases still faces challenges of lack of specific drugs as well as adverse drug reactions.However,Chinese medicine has shown unique advantages in preventing and treating liver diseases,among which Zhizi(Gardeniae Fructus)and its active ingredients have significant efficacy in treating various types of liver diseases.Modern pharmacological studies have also shown that Zhizi(Gardeniae Fructus)exhibits anti-inflammatory,anti-thrombotic,anti-viral,anti-oxidation,regulating blood lipids and other effects,which can alleviate symptoms of multiple liver diseases such as non-alcoholic fatty liver disease,liver cirrhosis,liver injury,and liver cancer.This paper summarizes the recent research on the mechanism of action of Zhizi(Gardeniae Fructus)in various liver diseases,aiming to provide a reference for further research and clinical application of Zhizi(Gardeniae Fructus)in the prevention and treatment of liver diseases.
Zhizi(Gardeniae Fructus)geniposideliver injuryliver fibrosisliver cancer