Retrospective study on TCM pattern characteristics of people with elevated blood lipid margins
Objective To explore the core pathogenesis and TCM pattern characteristics in people with elevated blood lipid margins,and to provide reference for early prevention and treatment of dyslipidemia in TCM.Methods A total of 1 404 individuals with elevated blood lipid margins who met the inclusion and exclusion criteria from December 2018 to December 2020 were recruited,including 720 females and 684 males,aged between 28 and 65 years old.Information including gender,age,blood pressure,height,weight,body mass index,fasting blood glucose,blood uric acid,triglycerides,cholesterol,low-density lipoprotein,high-density lipoprotein,as well as other TCM symptoms and signs was collected to establish a database of abnormal blood lipid levels.Frequency statistics,factor analysis,and systematic clustering were employed to explore the core pathogenesis and pattern characteristics.Results The top five TCM symptoms and signs with the highest frequency were tidal fever due to warm dampness,dry mouth,clear urine,bitter taste,and obesity;seven common factors were extracted by factor analysis,namely,spleen deficiency with blood stasis pattern,damp heat damaging yin pattern,damp heat affecting the spleen pattern,damp heat with stomach retention pattern,spleen deficiency with phlegm dampness pattern,phlegm heat damaging yin pattern,and stomach heat with spleen deficiency pattern;systematic clustering was divided into six TCM patterns and one state,namely,phlegm dampness accumulating in the spleen pattern,damp heat in the large intestine pattern,qi-yin injury with blood stasis pattern,yang qi insufficiency pattern,spleen and stomach deficiency pattern,three jiao damp heat pattern,and obesity.Conclusion The pattern distribution in people with elevated blood lipid margins mainly includes phlegm dampness accumulating in the spleen pattern,damp heat in the large intestine pattern,qi-yin injury with blood stasis pattern,yang qi insufficiency pattern,spleen and stomach deficiency pattern,three jiao damp heat pattern,and their manifestation of physical obesity.
elevated blood lipid marginspattern distributionfrequency statisticsfactor analysissystematic clusteringmiddle jiao fullness and internal heatpreventing a disease before it arises