Clinical observation on the effects of modified Tounong Powder combined with mild moxibustion on wound healing after anorectal abscess surgery
Objective To explore the clinical efficacy of modified Tounong Powder combined with mild moxibustion on wound healing after anorectal abscess surgery.Methods A total of 120 patients with anorectal abscess in the Anorectal Department of Danzhou Hospital of Chinese Medicine from January 2021 to December 2023 were selected and divided into observation group(n=60)and control group(n=60)by simple randomization method.Incision and drainage were performed in both groups,and the control group received routine treatment according to anorectal department protocols after surgery,while the observation group was given modified Tounong Powder(one dose per day,for 14 days)and mild moxibustion(one session per day,for 14 days)on the basis of the control group.The clinical effect,wound pain scores(on the 1st,3rd,7th,and 14th days after surgery),wound exudation scores(on the 3rd,7th,and 14th days after surgery),perianal skin edema scores(on the 3rd,7th,and 14th days after surgery),wound granulation tissue scores(on the 3rd,7th,and 14th days after surgery),wound healing time,serological indicators[tumor necrosis factor-α(TNF-α),interleukin-6(interleukin-6),vascular endothelial growth factor(VEGF),and epidermal growth factor(EGF)](on the 1st,7th,and 14th days after surgery),and safety were compared between the two groups.Results The cure rate of in observation group(78.33％)was higher than that in the control group(53.33％)(P＜0.05).Compared with the first day after surgery,the wound pain scores in both groups was lower on the 7th and 14th day after surgery(P＜0.05),and those of the observation group was lower than those in the control group(P＜0.05).Compared with the 3rd day after surgery,the wound exudation,perianal skin edema,and wound granulation tissue scores of the two groups were lower on the 7th and 14th days after surgery(P＜0.05),and those of the observation group were lower than those in the control group(P＜0.05).The wound healing time of observation group was shorter than that in the control group(P＜0.05).Compared with the 1st day after surgery,the serum levels of TNF-α and IL-6 in both groups were decreased on the 7th and 14th days after surgery(P＜0.05),and the levels in the observation group were lower than the control group(P＜0.05).Conversely,the serum levels of VEGF and EGF in both groups were higher on the 7th and 14th days after surgery(P＜0.05),and the levels in the observation group were higher than the control group(P＜0.05).In the course of treatment,there were no obvious adverse reactions on the local and systemic wounds in the two groups.Conclusion Modified Tounong Powder combined with mild moxibustion can relieve wound pain,reduce wound exudation,promote wound healing,reduce inflammatory response,and increase serum VEGF and EGF levels in patients with anorectal abscess after surgery,with significant effects and high safety.
万方数据
维普
