Depression is a common clinical emotional disorder and an important public health problem in today's society.Chinese medicine has rich clinical experience and definite therapeutic efficacy in treating depression,but its mechanism of action is not yet fully clear.Scientific and reliable animal models that integrate disease and pattern is crucial for exploring the mechanisms related to preventing and treating depression with Chinese medicine.By querying relevant Chinese database,this study has summarized six kinds of animal models of depression integrating disease and pattern,including models for liver qi stagnation pattern,liver stagnation with spleen deficiency pattern,kidney yin deficiency pattern,kidney yang deficiency pattern,yin deficiency-induced internal heat pattern,and qi deficiency pattern.The specific modeling methods and evaluations of these six integrated disease and pattern models have been briefly elucidated.Additionally,the shortcomings of the current research have been proposed and analyzed in order to provide reference for researchers.
关键词
抑郁症/病证结合/动物模型/中医证候/模型评价/研究进展
Key words
depression/integrating disease and pattern/animal model/TCM pattern/model evaluation/research progress
维普
万方数据