Theoretical connotation and therapeutic strategies of migraine from the perspective of ZHU Danxi's Differentiation of "left and right"
Based on Zhu Danxi's elaboration on treating migraine,which posits that"the left side is related to wind,and the right side to phlegm",combining the ancient understanding progression from"left and right"to"east and west"and further to"liver and lung",along with ZHU Danxi's theoretical ideas of"ministerial fire","yang is often excessive,while yin is often insufficient",and"when qi is in excess,it transforms into fire",it is believed that the core pathogenesis of migraine lies in the"dysfunction of liver blood and lung qi".The pathogenesis of left-sided migraine involves reckless stirring of ministerial fire,upward flaming of blood heat,and the combination with pathogenic wind;or gradual consumption of liver blood,failure of deficient blood to nourish,and emptiness of the cerebral vessels.The pathogenesis of right-sided migraine includes that excessive qi leads to stagnation,which subsequently transforms into fire,resulting in the upward flaming of fire-heat;or malfunction of the lung leads to accumulation of phlegm in the spleen,obstructing the meridians.Therefore,the therapeutic methods focus on dispersing and replenishing liver blood,while descending and clearing lung qi.Depending on the situation,herbs such as Bohe(Menthae Haplocalycis Herba)and Jingjie(Schizonepetae Herba)are used to disperse wind-cold and clear blood heat,Danggui(Angelicae Sinensis Radix)and Chuanxiong(Chuanxiong Rhizoma)to warm and nourish liver blood,Huangqin(Scutellariae Radix)to clear lung fire,and Cangzhu(Atractylodis Rhizoma)and Banxia(Pinelliae Rhizoma)to resolve phlegm and circulate qi.Additionally,based on the asymmetry of the human body and different therapeutic strategies during onset,the theory of asymmetric running of meridians is proposed,wherein the left side of the head is governed by ascending liver qi,while the right side by descending lung qi.Guided by this running mode of meridians,clinicians can assess the depth of headaches and the affected organs and choose appropriate medications based on the"left or right"onset of migraines.In summary,the differentiation of the"left and right"onset of migraines can guide the diagnosis and treatment of this disease,providing valuable insights for Chinese medicine clinical practice.
migraineleft and rightliver blood and lung qiasymmetric running of meridiansZHU Danxitheory of ministerial fireyang is often excessive,while yin is often insufficientwhen qi is in excess,it transforms into fire