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间充质干细胞外泌体在骨肉瘤治疗中的研究进展

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阐述间充质干细胞外泌体(MSC-Exos)在骨肉瘤(OS)治疗中的研究进展.通过查阅近年的相关文献,综述OS的研究现状、发病机制和潜在治疗靶点,MSC-Exos的生物学特性和功能,以及MSC-Exos在OS的靶向治疗、肿瘤耐药性和作为药物递送载体等方面的研究进展.结果表明:MSC-Exos作为一种新兴的生物治疗剂,在OS治疗领域具有广阔的应用前景.
Research Progress of Mesenchymal Stem Cell-Derived Exosomes in Treatment of Osteosarcoma
To elucidate the research progress of mesenchymal stem cell-derived exosomes(MSC-Exos)in the treatment of osteosarcoma(OS).By reviewing recent relevant literature,summarizes the current status,path-ogenesis,and potential therapeutic targets of OS,the biological characteristics and functions of MSC-Exos,as well as the research progress of MSC-Exos in the OS targeted therapy,tumor drug resistance and as a drug de-livery carrier.The results show that MSC-Exos,as a novel biological therapeutic agent,has broad application prospects in the field of treatment of OS.

mesenchymal stem cellsexosomesosteosarcomatargeted therapytumor resistance

王福财、刘卓晟

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华侨大学医学院,福建泉州 362021

间充质干细胞 外泌体 骨肉瘤 靶向治疗 肿瘤耐药性

2025

华侨大学学报(自然科学版)
华侨大学

华侨大学学报(自然科学版)

影响因子:0.329
ISSN:1000-5013
年,卷(期):2025.46(1)