Two Cases of Non-mediastinal T-lymphoblastic Lymphoma and Review of the Literature
Objective To investigate the clinical and imaging features of non-mediastinal T-lymphoblastic lymphoma(T-LBL)in order to improve the understanding of T-LBL.Methods The clinical presentation,laboratory tests,imaging and pathological results of two cases of non-mediastinal T-LBL and the relevant literatures were reviewed and analyzed.Results Multiple superficial lymph nodes enlargement was seen in case 1,and left extraocular muscles thickening was demonstrated in case 2,respectively.B symptoms could be seen in case 1.Mild to moderate enlargement of multiple lymph nodes in both axillae,supraclavicular area,mediastinum,intra-abdominal cavity,retroperitoneal and bilateral inguinal area were found in case 1.The clinical symptom of case 2 was blurred vision of left eye for two months.Diffuse thickening of left extraocular muscles were found,mostly involve the abdomen portion,and the optic nerve was surrounded and the left parasellar area was involved.Cases were confirmed of T-LBL by needle biopsy,immunohistochemistry,bone marrow aspiration and other examinations.Conclusion Non-mediastinal T-LBL is rare in clinical practice,commonly occurred in young adult males.Multiple lesions with polycentric growth mode were seen on CT and MR images,the lesions were regular in morphology,with homogeneous density/signal and homogeneous enhancement after contrast enhanced,mild to moderate enhancement was found.
万方数据
维普
