Objective To comprehend the primary clinical symptoms,prognosis,and therapy of well-differentiated papillary mesothelioma(WDPM).Methods We reviewed the pertinent research and the patient's peritoneal hyperdifferentiated papillary mesothelioma data.Results The patient mainly presented with intestinal obstruction.On the mesenteric surface of the small intestine,several tiny nodules can be recognized.Inside the nodules,which were observed under a microscope,were papillae bordered with a single layer of rectangular mesothelial cells,each having a fibrovascular core and a consistent mesothelial cell shape,including round nuclei and short nucleoli.CR(+),D2-40(+),CK5/6(weak+),CK7(+),CK19(+),Ki-67(1％+),P53(50％+),EMA(-),and CEA(-)were the immunohistochemical findings.The patient had conservative treatment and was monitored after receiving a preliminary diagnosis of peritoneal highly differentiated papillary mesothelioma.Conclusion The WDPM is an uncommon mesothelial tumor with a low-grade malignant potential and no distinguishing symptoms.There is no agreement on the conventional treatment of WDPM,and the diagnosis primarily relies on operative exploration,pathological biopsies,and immunohistochemical analysis.
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