Application of Combined Detection of Serum CK-MB,NT-proBNP,PCT,and CRP in the Diagnosis of Kawasaki Disease in Infants and Young Children
Objective To study the application value of combined detection of serum creatine kinase isoenzyme(CK-MB),N-terminal proBNP precursor,procalcitonin(PCT),and C-reactive protein(CRP)in the diagnosis of Kawasaki disease in infants and young children.Methods 96 infants and young children with Kawasaki disease admitted to Zhengzhou People's Hospital from January 2021 to December 2022 were selected and included in the Kawasaki disease group.50 healthy infants and young children who underwent physical examination at the same time were included as the control group.96 infants and young children with Kawasaki disease were divided into a CAL group and a CAL group based on the occurrence of coronary artery disease(CAL).Detect the levels of serum CK-MB,NT proBNP,PCT,and CRP,and analyze the diagnostic value of serum CK-MB,NT proBNP,PCT,and CRP for the occurrence of CAL in infants and young children with Kawasaki disease.Results The ROC curve results showed that the AUC values of serum CK-MB,NT-proBNP,PCT,CRP,and combined detection for diagnosing Kawasaki disease in infants and young children were 0.766,0.722,0.726,0.767,and 0.823,respectively,which have certain diagnostic value.The AUC values for diagnosing CAL in infants and young children with Kawasaki disease were 0.821,0.830,0.838,0.887,and 0.912,respectively,which have certain diagnostic value.Conclusion The combined detection of serum CK-MB,NT proBNP,PCT,and CRP has high application value in the diagnosis of Kawasaki disease in infants and young children.
万方数据
维普
