首页|依达拉奉与奥扎格雷钠联合治疗脑梗死的效果及对NIHSS评分影响

依达拉奉与奥扎格雷钠联合治疗脑梗死的效果及对NIHSS评分影响

扫码查看
目的 分析依达拉奉与奥扎格雷钠联合用药方案治疗脑梗死的临床效果及对患者NIHSS评分影响。方法 选取我院2022年1月至2023年12月期间收治的120例脑梗死患者作为研究对象,遵循随机数字表法分组原则将患者分为参照组(60例)与实验组(60例)。参照组给予奥扎格雷钠治疗,实验组在参照组基础上联合依达拉奉治疗。观察两组治疗前后NIHSS评分、氧化应激指标及疗效。结果 治疗后,实验组NIHSS评分显著低于参照组(P<0。05);实验组氧化应激指标改善效果优于参照组(P<0。05);实验组治疗总有效率96。67%高于参照组的80。00%(P<0。05)。结论 在脑梗死治疗中,依达拉奉与奥扎格雷钠联合治疗的效果更好,不仅可以更有效的改善患者神经功能,降低机体的氧化应激状态,同时也能提高临床治疗有效性,改善患者预后。
Effect of Edaravone Combined with Sodium Ozagrel in the Treatment of Cerebral Infarction and Its Influence on NIHSS Score of Patients
Objective To analyze the clinical effect of edaravone combined with ozagrel sodium in the treatment of cerebral infarction and its influence on NIHSS score.Methods 120 patients with cerebral infarction admitted to our hospital from January 2022 to December 2023 were selected as the research objects,and were divided into the reference group(60 cases)and the experimental group(60 cases)according to the principle of random number table.The reference group was treated with sodium ozagrel,and the experimental group was treated with edaravone based on the reference group.NIHSS score,oxidative stress index and curative effect were observed before and after treatment.Results After treatment,the experimental group NIHSS score significantly lower than that of control group(P<0.05);the improvement of oxidative stress index in experimental group was better than that in reference group(P<0.05).The total effective rate of the experimental group was 96.67%higher than that of the reference group(80.00%)(P<0.05).Conclusion In the treatment of cerebral infarction,Edaravone combined with sodium ozagrel has a better effect,which can not only improve the neurological function of patients more effectively,reduce the oxidative stress state of the body,but also improve the effectiveness of clinical treatment and improve the prognosis of patients.

EdaravoneSodium OzagrelCerebral InfarctionNIHSS ScoreSerum Oxidative Stress indexCurative Effect

夏中杰、路雪燕、位霞飞、武帆、张贵艺、程璇

展开 >

新乡医学院第二附属医院(河南新乡 453002)

郑州大学第一附属医院(河南郑州 450052)

依达拉奉 奥扎格雷钠 脑梗死 NIHSS评分 氧化应激指标 疗效

2025

罕少疾病杂志
深圳市卫生局

罕少疾病杂志

影响因子:0.583
ISSN:1009-3257
年,卷(期):2025.32(1)