The Diagnostic and Differential Value of TG,TPOAb,TGAb,CEA Combined Detection for Benign and Malignant Thyroid Nodules
Objective To explore and analyze the diagnostic and differential value of combined detection of thyroglobulin(TG),thyroid peroxidase antibody(TPOAb),thyroglobulin antibody(TGAb),and carcinoembryonic antigen(CEA)for benign and malignant thyroid nodules.Methods From January 2022 to April 2024,96 patients with thyroid nodules admitted to our hospital,including 59 benign and 37 malignant nodules,were selected and divided into the benign group and the malignant group in turn.The levels of TG,TPOAb,TGAb and CEA in the two groups were detected and compared,and the diagnostic and differential value of combined detection was analyzed.Results The levels of TG,TPOAb,TGAb,and CEA in the benign group were significantly lower than those in the malignant group(P＜0.05);The positive rates of TG,TPOAb,and TGAb in the benign group were lower than those in the malignant group(P＜0.05);According to ROC curve analysis,the sensitivity and specificity of the combined detection of TG,TPOAb,TGAb,and CEA were 91.89％and 94.92％,respectively.The area under the curve(AUC)was 0.942,and the Youden index was 0.863.The diagnostic and differential efficacy of the combined detection was significantly higher than that of the single detection(P＜0.05).Conclusion The combined detection of TG,TPOAb,TGAb and CEA has high diagnostic and differential value,which can be used to distinguish the good and evil characteristics of thyroid nodules in clinic.
万方数据
维普
