A Study on the Efficacy of Sequential Mechanical Ventilation Based on Lung Infection Control Window Combined with Spontaneous Breathing Test Timing in the Treatment of Acute Exacerbation of COPD Patients and Its Impact on Lung Function and Blood Gas Indica
Objective To explore the clinical study of sequential mechanical ventilation in the treatment of patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD)based on pulmonary infection control window(pic-w)and spontaneous breathing test(SBT).Methods A retrospective analysis was conducted on 86 patients with acute exacerbation of COPD treated with invasive non-invasive sequential mechanical ventilation in the intensive care unit(ICU)of the author's hospital.According to the selection of switching points,43 patients were divided into a control group,and PIC was selected to determine the timing of invasive non-invasive sequential mechanical ventilation treatment.In the experimental group,43 patients were selected to use PIC-W+SBT to determine the timing of invasive non-invasive sequential mechanical ventilation treatment.Compare the therapeutic effects of two groups.Results After treatment,the FEV1,FVC values,PaCO2,and SaO2 of the two groups of patients were significantly higher than before treatment,and the experimental group was higher than the control group(P＜0.05).The PaO2 value,re intubation rate,mortality rate,and incidence of complications in the experimental group were lower than those in the control group after treatment(P＜0.05).The total mechanical ventilation time and ICU hospitalization time in the experimental group were shorter than those in the control group(P＜0.05).Conclusion Sequential mechanical ventilation based on lung infection control window combined with spontaneous breathing test timing is well tolerated in patients with acute exacerbation of chronic obstructive pulmonary disease,reducing the rate of re intubation and mortality.It has a positive effect on improving lung function,blood gas indicators,and reducing complications,and can be promoted and applied in clinical practice.
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维普
