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Ⅱ型心肌梗死的临床特点及预后影响因素分析

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目的 分析Ⅱ型心肌梗死(T2MI)的临床特点及影响其不良预后的危险因素。方法 选取2021年3月至2023年1月时间内我院收治的T2MI患者182例,随访观察1年,根据随访结果将患者分为死亡组(n=48例)和存活组(n=134例)。分析T2MI患者的临床特点,比较2组患者临床基本资料,采用单因素和多因素Logistic回归分析模型分析影响T2MI患者不良预后的危险因素。结果 50岁以上患者居多,70~80岁占比最高达到37。91%,女性患者比例高于男性,具有吸烟史的患者占比26。92%,自身基础疾病较多,1年内死亡率达到26。37%。死亡组与存活组的性别、体质量(BMI)、合并糖尿病、吸烟史、左心室舒张末期内径(LVEDD)及低密度脂蛋白胆固醇(LDL-C)、白细胞计数(WBC)、血红蛋白(HB)、血清肌酐(Scr)、C-反应蛋白(CRP)水平比较,差异无统计学意义(P>0。05);死亡组年龄、心律失常患者占比、高血压患者占比、心力衰竭分级(Killip分级)中≥Ⅱ级占比及肌钙蛋白(cTn)、脑钠肽(NT-proBNP)水平均高于存活组(P<0。05),Killip分级中Ⅰ级占比、LVEF水平则低于存活组(P<0。05);经Logistic回归分析模型,结果显示,高龄、心律失常、高血压、NT-proBNP及cTn高水平均是导致患者死亡的危险因素(P<0。05)。结论 T2MI患者高龄、女性患者占比较大,自身合并基础病多,死亡率高。高龄、合并高血压及高浓度NT-proBNP、cTn水平均为影响T2MI不良预后的危险因素。
Analysis of Clinical Features and Prognostic Factors of Type 2 Myocardial Infarction
Objective To analyze the clinical features of type 2 myocardial infarction(T2MI)and the risk factors affecting its poor prognosis.Methods 182 T2MI patients admitted to our hospital from March 2021 to January 2023 were selected and followed up for 1 year.According to the follow-up results,the patients were divided into death group(n=48 cases)and survival group(n=134 cases).The clinical characteristics of T2MI patients were analyzed,and the basic clinical data of the two groups were compared.Univariate and multivariate Logistic regression analysis models were used to analyze the risk factors affecting the poor prognosis of patients with T2MI.Results The majority of patients were over 50 years old,and the proportion between 70 and 80 years old reached 37.91%.The proportion of female patients was higher than that of men.Patients with a history of smoking accounted for 26.92%.Gender,body mass(BMI),diabetes mellitus,smoking history,infarct vessels,number of lesions,left ventricular end-diastolic diameter(LVEDD)and low density lipoprotein cholesterol(LDL-C),white blood cell count(WBC),hemoglobin(HB),serum creatinine(Scr),C-reactive protein(CRP)water in the death and survival groups There was no statistical significance(P>0.05).Age,proportion of patients with arrhythmia,proportion of patients with hypertension,proportion of≥Ⅱ in heart failure grading(Killip grading)and the levels of troponin(cTn)and brain natriuretic peptide(NT-proBNP)in death group were higher than those in survival group(P<0.05).The proportion and LVEF level of Killip grade Ⅰ were lower than those of survival group(P<0.05).Logistic regression analysis model showed that old age,arrhythmia,hypertension,high levels of NT-proBNP and cTn were risk factors for death(P<0.05).Conclusion Elderly and female patients accounted for a large proportion of T2MI patients,with more underlying diseases and high mortality.Old age,hypertension and high concentration of NT-proBNP and cTn are risk factors for poor prognosis of T2MI.

Myocardial InfarctionMyocardial injuryRisk Factor

李拉拉、杨彦平、杨剑、段晓静、陈光平、刘微

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首钢水钢医院心血管/高血压内科(贵州六盘水 553000)

首钢水钢医院脑科病区(贵州六盘水 553000)

贵州省人民医院心血管内科(贵州贵阳 550000)

心肌梗死 心肌损伤 危险因素

2025

罕少疾病杂志
深圳市卫生局

罕少疾病杂志

影响因子:0.583
ISSN:1009-3257
年,卷(期):2025.32(1)