Application of Ultrasound-guided Coarse Needle Biopsy in the Diagnosis of Early Invasive Lobular Carcinoma of the Breast
Objective To analyze the application value of ultrasound-guided coarse needle biopsy in the diagnosis of early invasive lobular carcinoma of the breast.Methods 180 patients with early breast cancer were selected from our hospital from April 2018 to December 2022.According to the results of postoperative histopathology,all patients were divided into early invasive lobular breast cancer(lobular cancer group,n=70 cases)and other early breast cancer(control group,n=110 cases).All patients underwent ultrasound-guided histology and fine-needle aspiration before operation.At the same time,the value of ultrasound-guided histology and fine-needle aspiration was analyzed by comparing with the results of postoperative histopathology.Results The results of ultrasound-guided fine needle aspiration histopathology showed that 50 patients were early invasive lobular breast cancer,and 130 patients were other early breast cancer.The results of ultrasound-guided thick needle biopsy showed that 61 patients were early invasive lobular breast cancer,and 119 patients were other early breast cancer.The diagnostic sensitivity of ultrasound-guided coarse needle aspiration was significantly higher than that of ultrasound-guided fine needle aspiration(P<0.05).The results of ultrasound-guided biopsy showed that the positive expression rate of HER-2 in lobular carcinoma group was significantly higher than that in control group(P<0.05).Conclusion In the diagnosis of early invasive lobular carcinoma of the breast,ultrasound-guided coarse needle biopsy has a high diagnostic sensitivity,and the patients have a high positive expression rate of HER-2.
Early StageInfiltrating Lobular Carcinoma of BreastUltrasound GuidanceCoarse Needle PuncturePathological Examination