Curative Effect of Kuhuang Injection Combined with Diamine Glycyrrhizinate Injection on Patients with Acute Jaundice Viral Hepatitis and Its Influencing Factors
Objective To observe the efficacy of bitter yellow injection combined with glycyrrhizic acid diamine injection in the treatment of acute jaundice viral hepatitis.Methods A total of 80 patients with acute jaundice viral hepatitis admitted to our hospital from July 2022 to July 2023 were divided into reference and research groups,and all were treated with glycyrrhizinatediamine injection,and the study group was combined with bitter yellow injection,and the clinical efficacy,adverse reactions,symptom scores and liver function were observed and compared.conducted a risk factor analysis to investigate the independent risk factors affecting efficacy.Results(1)The total effective rate of treatment(97.50％)was higher than that in the control group(85.00％),and the comparison was statistically significant(P＜0.05).(2)The incidence of adverse reactions in the study group(7.50％)was slightly lower than that in the control group(12.50％),but the comparison was not statistically significant(P＞0.05).(3)The total score of the clinical symptom performance study group(4.60±2.12 points)was lower than that of the reference group(8.49±3.28 points),and the comparison was statistically significant(P＜0.05).(4)The liver function TBIL,DBIL,ALT,AST and γ-GT levels(18.13±4.21μmol/L,18.34±4.14μmol/L,152.71±16.48U/L,140.68±12.51U/L,110.91±42.57U/L)were lower than those in the reference group(24.62±4.23pmol/L,24.28±4.65μmol/L,171.84±).20.59U/L,161.44±17.07U/L,134.62±51.04U/L),all of which were statistically significant(P＜0.05);The ALB level(40.32±2.84 g/L)was not significantly compared with the reference group(39.95±2.86 g/L)(P＞0.05).Risk factor analysis revealed that age＞35(OR:5.488,95％CI:1.432-21.027,P=0.013),disease duration＞1 year(OR:3.682,95％CI:1.168-11.611,P=0.026),pre-treatment ALT＞540U/L(OR:4.199,95％CI:1.369-12.879,P=0.012),and treatment regimen(OR:4.123,95％CI:1.273-13.348,P=0.018)were independent risk factors affecting efficacy.Conclusion The treatment of acute jaundice viral hepatitis with bitter yellow injection combined with glycyrrhizate diamine injection can help patients improve liver function and accelerate the disappearance of symptoms,which is worthy of further promotion.
Bitter Yellow InjectionGlycyrrhizinatediamine InjectionAcute Jaundice Viral HepatitisSymptom ScoresLiver Function
万方数据
维普
