Objective To Analyze and explore the application value of DWI,DCE combined with PSA detection in the clinical diagnosis of prostate cancer.Methods We selected 80 prostate cancer patients admitted to our hospital from June 2021 to February 2023 as the research subjects and set them as the observation group.At the same time,we also selected 85 prostate hyperplasia(BHP)patients who received diagnosis and treatment in our hospital during the same period as the control group,and conducted a retrospective analysis of their clinical data.Both groups of patients used pathological diagnosis results as the gold standard,and performed routine MRI,DCE-MRI,DWI,and serum PSA tests for both groups of patients.The role and value of different detection methods in clinical diagnosis and treatment were compared and ana lyzed.Results Among the 80 cases of prostate cancer,34 cases belong to central region cancer and 46 cases belong to peripheral zone cancer.There was a statistical difference in the distribution of time signal intensity curve types between the control group and the observation group(P＜0.05);According to the DWI imaging results,the signal of prostate cancer lesions is generally significantly high,and the ADC value is low,with an average ADC value of(0.69±0.12)×10-3mm2/s;Prostate hyperplasia nodules are mainly slightly high signal,with a small portion indicating high signal.The ADC value has decreased,with an average ADC value of(1.04±0.20)×10-3mm2/s.There is a statistical difference in ADC value between the two groups(P＜0.05).The combined diagnostic method of DWI+DCE+PSA for prostate cancer has the highest accuracy,sensitivity,specificity,positive predictive value,and negative predictive value.Compared with other diagnostic methods,the differences are statistically significant(P＜0.05).Condusion DWI and DCE have certain clinical value in distinguishing between prostate cancer and benign prostatic hyperplasia,and the combination of PSA has a significant diagnostic effect on prostate cancer,which helps guide the rational selection of clinical treatment plans.
维普
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