Objective To investigate the relationship between the number of lymph nodes dissected during radical operation and long-term recurrence and death in patients with stage Ⅱ～Ⅲ gastric cancer.Methods The clinical data of 186 patients with stage Ⅱ～Ⅲ gastric cancer who underwent radical operation in our hospital from December 2018 to December 2020 were retrospectively analyzed,and the patients were followed up until December 2022.According to the requirements of the International Union against Cancer and the number of intraoperative lymph nodes dissection,the patients were divided into groups≥25(88 cases)and groups 15-25(98 cases).COX risk regression was used to analyze the relationship between the number of lymph nodes dissection and long-term recurrence and death in patients with gastric cancer,with gender,age,tumor size,tumor site and other variables controlled.Results After 2 years of follow-up,61 cases of gastric cancer recurred and 38 cases died.The recurrence rate and mortality rate were 32.80％and 20.43％,respectively.Univariate analysis showed that the recurrence rate of gastric cancer in≥25 patients was 25.00％,which was lower than that in 15-25 patients(39.80％)(P＜0.05).The mortality rate of≥25 patients was 12.50％lower than that of 15-25 patients(27.55％)(P＜0.05).COX risk regression analysis showed that the number of lymph nodes dissected was a risk factor for long-term recurrence(HR=2.776,P＜0.05)and death in patients with gastric cancer(HR=1.669,P＜0.05).Conclusion The number of lymph nodes dissected during radical operation is significantly correlated with long-term recurrence and death in patients with stage Ⅱ～Ⅲ gastric cancer,and the risk of long-term recurrence and death is lower in patients with more than 25 lymph nodes dissected.
Gastric CancerRadical OperationNumber of Lymph Nodes DissectedLong-term RecurrenceDeathPathological Stage
维普
万方数据
