Total Cholesterol/High Density Lipoprotein Cholesterol Ratio to Predict In-stent Restenosis in Patients with Arteriosclerosis Obliterans
Objective To investigate the predictive value of total cholesterol/high density lipoprotein cholesterol(TC/HDL-C)ratio for in-stent restenosis after lower limb arteriosclerosis obliterans(ASO)surgery.Methods The clinical data of 51 patients with in-stent restenosis after ASO in lower limbs admitted to the General Hospital of Shenma Medical Group in Pingmei from January 2019 to August 2022 were collected and included in the restenosis group.In addition,the clinical data of 51 patients with no in-stent restenosis after lower limb ASO were collected and included in the non-restenosis group.All patients were followed up for 3 months after operation.The baseline data of the patients were reviewed by the researchers and detailed statistics were made.The TC/HDL-C ratio of the two groups was observed,and the relationship between TC/HDL-C ratio and in-stent restenosis after ASO was analyzed,and to explore the predictive value of TC/HDL-C ratio for in-stent restenosis after ASO.Results The ratio of TC and TC/HDL-C in the restenosis group was higher than that in the non-restenosis group,and HDL-C was lower than that in the non-restenosis group(P＜0.05).There was no significant difference in age,sex,body mass index,hypertension,diabetes,Fontaine stage,triglyceride(TG),low-density lipoprotein cholesterol(LDL-C),platelet count(PLT),and red blood cell count(RBC)between the two groups(P＞0.05).Through point binary correlation analysis,TC,TC/HDL-C ratio were positively correlated with in-stent restenosis after lower limb ASO(r＞0,P＜0.05),while HDL-C was negatively correlated with in-stent restenosis after lower limb ASO(r＜0,P＜0.05).Drawing the receiver's operating characteristic(ROC)curve,it was found that the area under the curve(AUC)of TC,HDL-C,TC/HDL-C ratio to predict the value of in-stent restenosis after lower limb ASO was more than 0.7,which had a certain predictive value,with the highest predictive value of TC/HDL-C ratio.Conclusion The ratio of TC/HDL-C is related to in-stent restenosis in patients with lower extremity ASO after operation,and this ratio can be used to predict the risk of in-stent restenosis after operation.
Lower Limbs Arteriosclerosis ObliteransTotal CholesterolHigh Density Lipoprotein Cholesterol
万方数据
维普
