首页|半永久导管与自体动静脉内瘘的老年维持性血液透析患者体内微炎症状态及血管内膜的影响研究

半永久导管与自体动静脉内瘘的老年维持性血液透析患者体内微炎症状态及血管内膜的影响研究

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目的 研究半永久导管与自体动静脉内瘘对老年维持性血液透析患者的影响。方法 选择2020年7月至2022年3月我院收住的80例老年维持性血液透析患者,通过随机列表法进行分组,分别40例,研究组采取自体动静脉内瘘,对照组选择半永久导管,对比两组肿瘤坏死因子-α(TNF-α)、白介素-6(IL-6)、超敏C反应蛋白(hs-CRP)、尿素氮(BUN)、血肌酐(Scr)、肌酐清除率(Ccr)、血红蛋白(Hb)、视黄醇结合蛋白(RBP)、清蛋白(ALB)、转铁蛋白(TRF)、阻力指数(RI)、最大内膜中层厚度(IMT)、并发症。结果 两组干预前的微炎症指标、血管内膜情况、肾功能、营养指标无差别(P>0。05),干预后研究组TNF-α、IL-6、hs-CRP、RI、最大IMT、BUN、Scr均低于对照组,但Ccr、Hb、RBP、ALB、TRF高于对照组(P<0。05)。研究组并发症7。50%少于对照组25。00%(P<0。05)。结论 自体动静脉内瘘在老年维持性血液透析中的效果更为理想,能够减轻患者机体中的微炎症状态,并改善血管内膜,调节机体营养水平,促进肾功能改善,并发症少,值得推广。
Impact Studies of Semi-permanent Catheter and Autogenous Arterio-venous Fistula on the In-vivo Micro-inflammation States and Tunica Intima for Ederly Maintenance Hemodialysis Patients
Objective To study the impact of semi-permanent catheter and autogenous arterio-venous fistula in elderly maintenance hemodialysis patients.Methods 80 elderly maintenance hemodialysis patients admitted from July 2020 to March 2022 in our hospital were selected.According to random permutation method,patients were assigned to study group(n=40,autogenous arterio-venous fistula)and control group(n=40,semi-permanent catheter).Group contrast results were obtained through tumor necrosis factor-α(TNF-α),lnterkeukin-6(IL-6),hypersensitivity C-reactive protein(hs-CRP),blood urea nitrogen(BUN),serum creatinine(Scr),creatinine clearance rate(Ccr),hemoglobin(Hb),retinol-binding protein(RBP),albumin(ALB),transferrin(TRF),resistance index(RI),maximum intima-media thickness(IMT)and surgical complications.Results Before intervention,there were no significant between-group differences about the micro-inflammation indicators,tunica intima conditions,renal function and nutritive indexes(P>0.05);after intervention,TNF-α,IL-6,hs-CRP,RI,maximum IMT,BUN and Scr values in the study group were significantly lower than those of control group;but Ccr,Hb,RBP,ALB and TRF levels were higher than those of control group(P<0.05);the surgical complication rate in the study group(7.50%)was lower than that of control group(25.00%)(P<0.05).Conclusion The autogenous arterio-venous fistula can better reduce the in-vivo micro-inflammation states and surgical complications,improve the tunica intima conditions,nutritional status and renal function for elderly maintenance hemodialysis patient.It is worthy of clinical promotion.

Micro-inflammation StatesSemi-permanent CatheterMaintenance HemodialysisAutogenous Arterio-venous Fistula

王静静

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安阳市第六人民医院肾内科(河南安阳 455000)

微炎症状态 半永久导管 维持性血液透析 自体动静脉内瘘

2025

罕少疾病杂志
深圳市卫生局

罕少疾病杂志

影响因子:0.583
ISSN:1009-3257
年,卷(期):2025.32(1)