Application Value of Thrombologram in Clinical Blood Transfusion Guidance and Coagulation Function Detection of Critically Ⅲ Traumatic Hemorrhage Patients
Objective To explore the value of thrombologram(TEG)for blood transfusion and coagulation function detection in critically ill patients.Methods A total of 104 patients with critical trauma hemorrhage admitted to our hospital from January 2021 to January 2023 were selected and randomly divided into control group and observation group,with 52 cases in each group.The control group guided blood transfusion according to routine coagulation indexes,and the observation group guided blood transfusion according to TEG results.The differences of coagulation function indexes and blood consumption between the two groups were compared,and TEG related indexes of the observation group were recorded before and after transfusion,and the relationship between TEG related indexes and routine coagulation indexes was analyzed.Results Before transfusion,there were no significant differences in the four items of coagulation and PLT between the two groups(P＞0.05).After blood transfusion,PT,APTT and TT in the observation group were lower than those in the control group(P＜0.05),while FIB was higher than that in the control group(P＜0.05).There was no statistical difference in PLT between the two groups after blood transfusion(P＞0.05).After transfusion,R value and K value of observation group were decreased compared with before transfusion,MA value,Angle and Cl value were increased compared with before transfusion(P＜0.05).The transfusions of frozen plasma and cryoprecipitate in the observation group were lower than those in the control group(P＜0.05),but there was no statistical difference in platelet transfusion between the two groups(P＞0.05).R value was positively correlated with APTT(r=0.328,P=0.036＜0.05),K value was negatively correlated with PLT(r=-0.389,P=0.001＜0.05),Angle was positively correlated with FIB and PLT(r=0.328,0.475,P=0.029,0.000＜0.05),MA was positively correlated with FIB and PLT(r=0.337,0.460,P=0.016,0.000＜0.05),Cl was positively correlated with FIB and PLT(r=0.235,0.348,P=0.020,0.014＜0.05).Conclusions TEG has a high guiding value in the transfusion treatment of critically ill patients with traumatic hemorrhage,and can detect and improve the coagulation abnormalities in patients.The relevant indicators of TEG have a certain correlation with the routine coagulation indicators,so it has a high clinical application value.
ThrombologramRoutine Coagulation Function TestCritical TraumaBleedingClinical Transfusion
万方数据
维普
