Objective:To evaluate the diagnostic value of serum cryptococcal capsular polysaccharide anti-gen(CrAg)in patients with suspected pulmonary cryptococcosis(PC)and analyze the factors influenc-ing the results.Methods:With pathological examination as the gold standard,the patients who were suspected of PC from January 2020 to November 2022 were selected.All patients were tested for se-rum CrAg.Results:Among the 234 patients suspected of PC,127 patients were finally diagnosed with PC and 107 patients were not.The sensitivity and specificity of serum CrAg in the diagnosis of PC were 65.4％and 86.0％,and its area under the curve(AUC)value(95％confidence interval)was 0.756(0.693 6,0.819 7).Significant differences were found in age,basic diseases,and types and dis-tribution of focal infections between the positive CrAg group and the negative CrAg group(P＜0.05).Conclusion:The detection of serum CrAg has a good specificity,which helps screen patients suspect-ed of pulmonary cryptococcosis for early diagnosis and treatment guidance.
Pulmonary CryptococcosisCryptococcus Capsular Polysaccharide AntigenSensi-tivitySpecificitySubject Specific Curve
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NSTL
万方数据
