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经枕部后纵裂-天幕入路切除松果体区及三脑室后部肿瘤

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目的:探讨经枕部后纵裂-天幕入路切除松果体区及三脑室后部肿瘤的经验和疗效.方法:回顾性分析2019年5月至2022年1月收治的12例松果体区及三脑室后部肿瘤患者的临床资料,观察其临床疗效.结果:病理结果示生殖细胞肿瘤3例(其中单纯生殖细胞瘤2例),星形细胞瘤2例,胶质母细胞瘤1例,松果体细胞瘤2例,表皮样囊肿3例,小细胞神经内分泌癌(肺来源)1例.肿瘤全切10例(83.3%),次全切2例(16.7%).无死亡病例.所有病例中,5例患者在切除肿瘤前行脑室外引流术,切除肿瘤后行三脑室底造瘘或终板造瘘缓解脑积水(其中2例在内镜下行造瘘术).术后1例患者脑室外引流管拔除不能,行脑室-腹腔分流术(VPS)治疗后好转.结论:经枕部后纵裂-天幕入路能够有效切除松果体区及三脑室后部肿瘤,切除肿瘤后可行三脑室底造瘘或终板造瘘缓解脑积水,值得推广.
Resection of tumors in pineal region and posterior third ventricle via occipital interhemispheric transtentorial approach
Objective:To investigate the clinical effect of resection of pineal region and posterior third ventri-cle tumors via occipital interhemispheric transtentorial approach.Methods:The clinical data of 12 pa-tients with the pineal region and posterior third ventricle tumors from May 2019 to January 2022 were re-trospectively studied,and the clinical curative effect was observed.Results:Pathological results showed that there were 3 cases of germ cell tumor(including 2 cases of single germinomas),2 cases of astrocytoma,1 case of glioblastoma,2 cases of pineocytomas,3 cases of epidermoid cysts,and 1 case of small cell neuroendocrine carcinoma(lung origin).Total tumor resection was performed in 10 cases(83.3%)and subtotal resection in 2 cases(16.7%).All cases were survived after operation.Among the 12 cases,5 cases underwent extraventricular drainage by drilling before tumor resection,and after tumor resection,they underwent a third ventriculostomy or endplate ostomy to relieve hydro-cephalus(2 of them underwent endoscopic ostomy).One patient still had hydrocephalus after the oper-ation,which was treated by a ventriculoperitoneal shunt(VPS).Conclusion:The occipital interhemi-spheric transtentorial approach can effectively remove the tumors in the pineal region and posterior part of the third ventricle.After the tumors are removed,the third ventriculostomy or endplate osto-my can be used to relieve hydrocephalus,which is worthy of promotion.

Pineal Region TumorsPosterior Third Ventricle TumorsSurgical ApproachMicrosurgery

王雷、刘仁忠、熊晓星、王峻、连海伟、余信远、邵灵敏、简志宏

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武汉大学人民医院神经外科 湖北 武汉 430060

松果体区肿瘤 三脑室后部肿瘤 手术入路 显微手术

湖北省卫生健康委员会科研项目

WJ2021M148

2024

武汉大学学报(医学版)
武汉大学

武汉大学学报(医学版)

CSTPCD
影响因子:0.959
ISSN:1671-8852
年,卷(期):2024.45(3)
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