Comparison of ultrasound-guided quadratus lumborum block and transverse versus abdominis plane block on analgesic effect after laparoscopic pancreatic cancer
Objective:To compare the effect of ultrasound-guided quadratus lumborum(QL)block and transverse abdominis plane(TAP)block for postoperative analgesia for laparoscopic pancreatic can-cer.Methods:Forty patients,15 males and 25 females aged 18-70 years,falling into ASA physical statusⅠ-Ⅲ,were included in this study from December 2021 to April 2022.According to the random number method,the patients were divided into the QL block group(group Q)and TAP block group(group T),with 20 cases in each group.The patients were transferred to post anesthesia care unit(PACU)after surgery,and group Q underwent bilateral quadratus lumborum block in PACU with the bilateral infusion of 0.25%ropivacaine 20 mL.Group T performed bilateral transverse abdominis plane block in PACU with a bilateral infusion of 0.25%ropivacaine 20 mL.The postoperative anal-gesic regimen in both groups was sufentanil patient-controlled intravenous analgesia(PCIA).The cu-mulative amount of sufentanil at the end of 1,6,12,24,36,and 48 hours after surgery,resting visu-al analogue scale(VAS),rescue analgesia,and related adverse effects(nausea,vomiting,respiratory depression),and block-related complications(puncture site infection,hematoma,local anesthetic poi-soning)were recorded.Results:At each time-pionts after surgery,the resting VAS pain score and cu-mulative amount of sufentanil of group Q were significantly lower than those of group T(P<0.05).There was no significant difference in the incidence of salvage analgesia and postoperative adverse ef-fects between the two groups.No complications including puncture site infection,hematoma,and lo-cal anesthetic poisoning occurred in both groups.Conclusion:Ultrasound-guided quadratus lumborum block can provide better postoperative analgesia and lower pain scores,and reduce postoperative opi-oid use in laparoscopic surgery for pancreatic cancer than transverse abdominis plane.