首页|多层螺旋CT在胃肠间质瘤危险度无创评估中的应用价值

多层螺旋CT在胃肠间质瘤危险度无创评估中的应用价值

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目的:分析胃肠道间质瘤(GISTs)的多层螺旋CT(MSCT)影像学表现,并探讨不同影像学特征与其生物学危险度之间的关系.方法:回顾性分析2017年2月至2022年1月期间在孝感市第一人民医院就诊并临床诊断为GISTs患者82例,最终经病理证实为GISTs且具有完整螺旋CT平扫及多期增强扫描资料者70例.分析所有患者的CT影像特征,包括:肿瘤发生部位、最大径、生长方式、形状、边界、强化程度、强化模式、有无出血坏死、有无钙化及转移等.患者根据病理危险度分为极低危、低危、中危、高危,比较不同危险分级之间影像特征差异.结果:70例病理确诊患者均为单发病灶,分布在胃、小肠、结直肠、肠系膜及网膜的病灶分别有41例(58.6%)、18例(25.7%)、7例(10%)、2例(2.85%)和2例(2.85%);病理危险度分级显示极低危、低危、中危及高危患者分别有6例、35例、20例和9例.MSCT对GISTs发生部分的定位诊断与病理结果具有很好的一致性.GISTs的MSCT影像学表现具有多样化特征,GISTs的危险度在肿瘤的发生部位、最大径、形态、强化方式、有无出血坏死、钙化及转移方面差异有统计学意义(P<0.05),而在肿瘤的生长方式、边界及强化程度方面差异未见明显统计学意义(P>0.05).结论:不同危险程度的胃肠间质瘤MSCT影像学表现存在一定的差异,尤其是肿瘤发生部位、最大径、形态及强化方式等征象在GISTs治疗前生物学危险性的无创评估中具有较高的应用价值.
Value of multislice CT applied in the non-invasive assessment of the risk of gastrointestinal stromal tumors
Objective:To analyze the multislice CT(MSCT)imaging presentation of gastrointestinal stro-mal tumors(GISTs)and to explore the relationship between different imaging features and their bio-logical risk.Methods:A retrospective analysis was performed on 82 patients who were clinically diag-nosed with GISTs between February 2017 and January 2022,in Xiaogan First People's Hospital,and 70 patients of them had complete spiral CT plain scan and multi-phase enhancement scan data.CT im-aging features of all the patients were analyzed,including the site of the tumor,maximum diameter,growth pattern,shape,border,degree of enhancement,enhancement pattern,presence of hemor-rhagic necrosis,presence of calcification,and metastases.The patients were classified into very low risk,low risk,intermediate risk,and high risk according to their pathological risk level.Results:All 70 pathologically confirmed patients had a single lesion,with 41(58.6%),18(25.7%),7(10%),2(2.85%),and 2(2.85%)lesions in the stomach,small intestine,colorectum,mesentery,and omen-tum,respectively;the pathological risk classification showed that 6,35,20 and 9 patients were at very low,low,medium and high risk,respectively.The localization of GISTs by MSCT was in good agreement with the pathological findings.The MSCT imaging manifestations of GISTs had di-verse features.Statistically significant differences were found in the risk level of GISTs in terms of tu-mor location,maximum diameter,morphology,mode of enhancement,presence of haemorrhagic ne-crosis,calcification and metastasis(P<0.05).However,there were no statistically significant differences in tumor growth pattern,border,and degree of enhancement(P>0.05).Conclusion:There are some differences in the MSCT imaging performance of gastrointestinal mesenchymal tu-mors with different risk levels,especially the signs of tumor location,maximum diameter,morpholo-gy,and enhancement pattern with high value in the non-invasive assessment of the biological risk of GISTs before treatment.

Gastrointestinal Stromal TumorsCTRisk FactorsImaging Signs

祝新平、龙清云、邓琪、柯永春、周攀、程泽爱

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孝感市第一人民医院放射影像科 湖北 孝感 432100

武汉大学中南医院介入诊疗中心 湖北 武汉 430071

胃肠道间质瘤 CT 危险因素 影像征象

2024

武汉大学学报(医学版)
武汉大学

武汉大学学报(医学版)

CSTPCD
影响因子:0.959
ISSN:1671-8852
年,卷(期):2024.45(5)
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