Objective:To explore the diagnostic value of endobronchial ultrasound-guided transbronchial needle aspiration(EBUS-TBNA).Methods:All EBUS-TBNA procedures performed at the Depart-ment of Respiratory and Critical Care Medicine,Zhongnan Hospital of Wuhan University from Sep-tember 2019 to August 2022 were summarized retrospectively.For the cases diagnosed as benign and unclassified lesions by EBUS-TBNA,the final diagnoses were determined by further invasive proce-dures or combined with treatment and clinical follow-up for at least 6 months.Results:Overall 618 pa-tients were included in the analysis with a mean age of(61.9±10.5)years,of whom 182(29.4%)were female and 436(70.6%)were male.The pathological specimens of 618 patients were successful-ly obtained by EBUS-TBNA,and the puncture success rate was 100%.The final diagnosis was 133 cases(21.5%)of benign lesions and 485 cases(78.5%)of malignant lesions.Among them,102(16.5%)of benign lesions and 464(75.1%)of malignant lesions were clearly diagnosed by EBUS-TBNA.The sensitivity,specificity,positive predictive value,negative predictive value,and accuracy of EBUS-TBNA were 91.3%(546/598),100%(20/20),100%(546/546),27.8%(20/72),91.6%(566/618),respectively.Only one case had active bleeding without serious complica-tions during the EBUS-TBNA procedure.Conclusion:The good diagnostic accuracy and safety of EBUS-TBNA in thoracic lesions are worthy of clinical promotion.
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