Objective:To analyze the clinical characteristics of neonatal sepsis with acute kidney injury(AKI).Methods:The patients diagnosed with neonatal sepsis admitted to Zhongnan Hospital of Wuhan University from January 2017 to December 2022 were divided into AKI group and non-AKI group.The clinical characteristics and mortality risk factors of the two groups were analyzed.Results:The incidence of AKI was 43.8％among the neonatal sepsis.Compared with the non-AKI group,the AKI group had smaller gestational age,lower birth weight,higher incidence of early-onset sepsis,Gram-negative bacterial infection,asphyxia,shock,maternal hypertensive disorder,and premature rupture of membrane(P＜0.05).The hospitalization time was longer(14(8,40)d vs 7(5,9)d,P＜0.01),and the mortality rate was higher(17.4％vs 0.0％,P＜0.01).Logistic analysis showed that asphyxia(OR=34.793,95％CI:15.188-69.402,P=0.012)and severe AKI(AKI stage 2-3)(OR=18.471,95％CI:1.932-50.141,P=0.014)were independent risk factors of neonatal sepsis mortality.Conclusion:Neonatal sepsis is easy to be complicated with AKI,and AKI children have longer hospital stay and higher mortality.
NETL
NSTL
万方数据
