首页|老年慢性阻塞性肺疾病患者营养风险与衰弱的横断面研究

老年慢性阻塞性肺疾病患者营养风险与衰弱的横断面研究

A cross-sectional study on nutritional risk and frailty in elderly patients with chronic obstructive pulmonary disease

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目的:了解老年慢性阻塞性肺疾病(COPD)患者的营养状况及衰弱情况,探讨老年COPD营养风险的影响因素及其营养状况与衰弱的相关性.方法:采用便利抽样的方法,选取2021年12月—2022年12月在武汉大学中南医院住院的老年COPD患者为研究对象,以营养风险筛查表(NRS2002)量表及FRAIL衰弱量表对老年COPD患者进行营养风险筛查及衰弱情况调查,并收集患者白蛋白、血清C反应蛋白指标,统计患者性别、年龄、体质量指数(BMI)、急性发病次数等参数.通过Kendall's tau-b分析患者衰弱状况与营养风险之间是否存在相关性,通过二分类Logistic回归来分析患者营养风险的影响因素.结果:120例老年COPD患者中,60.83%(73/120)的患者存在营养风险,65%(78/120)的患者存在衰弱,且其营养风险与衰弱存在正相关关系(r=0.739).营养风险组患者的衰弱得分、白蛋白水平、BMI等低于无营养风险组患者,而平均年龄、血清C反应蛋白水平、1年内急性发病次数等高于无营养风险组患者,差异均有统计学意义(P<0.05).衰弱状况、白蛋白水平、BMI、年龄、血清C反应蛋白与白蛋白比值(CAR)、急性发病次数等因素对老年COPD患者营养风险的发生有显著影响(P<0.05).结论:老年COPD患者营养风险及衰弱发生率高,其营养风险与衰弱情况相关,医护人员应重点关注老年COPD患者营养状况、白蛋白水平及炎症指标,并实施阶段化干预措施,动态化营养管理,降低衰弱率,改善患者的营养状态.
Objective:To investigate the nutritional status and frailty of elderly patients with chronic ob-structive pulmonary disease(COPD),and to explore the influencing factors of nutritional risk in elder-ly patients with COPD and the correlation between nutritional status and frailty.Methods:From De-cember 2021 to December 2022,convenience sampling was used to select elderly COPD patients hos-pitalized in Zhongnan Hospital of Wuhan University as the research objects.The Nutritional Risk Screening 2002(NRS2002)scale and FRAIL Frailty scale were used respectively to screen the nutri-tional risk and investigate the frailty of elderly COPD patients.Serum albumin,C-reactive protein,and other indicators of patients were collected,and parameters such as gender,age,body mass index(BMI),and the number of acute episodes of patients were counted.Kendall's tau-b was used to ana-lyze whether there was a correlation between frailty and nutritional risk,and binary logistic regression was used to analyze the influencing factors of nutritional risk.Results:Among the 120 elderly patients with COPD,60.83%(73/120)had nutritional risk and 65%(78/120)had frailty,and there was a positive correlation between nutritional risk and frailty(r=0.739).The frailty score,albumin level,and BMI of patients in the nutritional risk group were lower than those in the non-nutritional risk group,while the average age,serum C-reactive protein level,and the times of acute onset within one year were higher than those in the non-nutritional risk group(P<0.05).Age,BMI,times of acute on-set,albumin,serum C-reactive protein to albumin ratio(CAR),and frailty status had a significant im-pact on the occurrence of nutritional risk in elderly COPD patients(P<0.05).Conclusion:The nutri-tional risk is related to frailty in elderly patients with COPD.Medical and nursing staff should pay at-tention to the nutritional status,albumin level,and inflammatory indicators of the patients,and imple-ment phased intervention measures and dynamic nutritional management to reduce the rate of frailty and improve their nutritional status.

Chronic Obstructive Pulmonary DiseaseFrailtyNutritional StatusAlbuminSerum C-Reactive Protein

刘灵芳、方燕红、董佳、殷瑶、郑星、王睿珊、龚相丹、江红霞、程真顺、吴长蓉

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武汉大学中南医院呼吸与危重症医学科 湖北 武汉 430071

慢性阻塞性肺疾病 衰弱 营养状况 白蛋白 血清C反应蛋白

国家自然科学基金资助项目武汉大学中南医院护理学科培育课题资助项目

82070062HLXKPY202109

2024

武汉大学学报(医学版)
武汉大学

武汉大学学报(医学版)

CSTPCD
影响因子:0.959
ISSN:1671-8852
年,卷(期):2024.45(9)