Objective:To investigate the diagnostic accuracy of an artificial intelligence(AI)based chronic atrophic gastritis identification model in a real-world clinical environment.Methods:Patients undergo-ing gastroscopy at Wuhan Jiangxia District Hospital of Traditional Chinese Medicine from August 2022 to August 2023 were selected as a real-world test set to evaluate the generalization ability of the model.Endoscopists marked the biopsy sites according to the pathological results as chronic atrophic gastritis(CAG)and chronic non-atrophic gastritis(CNAG)and divided them into six anatomical re-gions:middle-upper body in retroflex view,fundus,antrum,angulus,middle-upper body in ante-grade view,lower body in antegrade view.The evaluation indicators included the recognition sensitivity,specificity,and accuracy of all cases and regional sampling.At the same time,three en-doscopists with different experience levels(low,medium,and high)were selected for a human-machine comparison,and the AI model's CAG identification ability was compared with that of endoscopists.Results:A total of 2 248 clear gastric cavity samples(CAG/CNAG,1 165/1 083)from 200 patients were collected as a real-world test set.On this test set,the AI model's recognition sensitivity,specificity,and accuracy were 92.27%(1 075/1 165),88.73%(961/1 083),and 90.57%(2 036/2 248),respectively.Compared with the results of three endoscopists with different experience levels,the identification accuracy of the AI model was equivalent to that of the senior en-doscopist and significantly better than that of the middle and junior endoscopists,with statistically sig-nificant differences.Conclusion:The AI model has stable diagnostic ability in clinical application and is equivalent to the level of senior endoscopists,which is expected to become an effective auxiliary tool for endoscopists.