肝硬化患者营养不良、肌肉减少症及脂质代谢异常的研究进展
Research advances in malnutrition,sarcopenia and abnormal lipid metabolism in patients with liver cirrhosis
敖紫淳 1朱洁 2吴清明2
作者信息
- 1. 武汉科技大学医学部医学院 湖北 武汉 430065;湖北省天门市第一人民医院消化内科 湖北 天门 431700
- 2. 武汉科技大学医学部医学院 湖北 武汉 430065;武汉科技大学医学部感染免疫与肿瘤微环境研究所/职业危险识别与控制湖北省重点实验室 湖北 武汉 430065
- 折叠
摘要
肝硬化作为各种慢性肝病发展的晚期阶段,具有高发病率和高死亡率.肝硬化患者常出现营养不良、肌肉减少症和脂质代谢异常,它们是影响肝硬化进展的危险因素,对肝硬化患者的预后造成严重负面影响.因此,需尽早识别和评估这些情况,并采取相应的干预措施.然而,目前还没有诊断肝硬化患者营养不良和肌肉减少症的标准化临床定义,临床医生需整合不同的评估方法.本文主要阐述肝硬化患者营养不良、肌肉减少症和脂质代谢异常的研究现状、病因和诊断方法,为进一步研究肝硬化患者营养不良、肌肉减少症及脂质代谢异常提供科学依据.
Abstract
As an advanced stage in the development of various chronic liver diseases,liver cirrhosis is characterized by high morbidity and mortality.Patients with cirrhosis commonly present with malnutrition,sarcopenia,and lipid metabolism disorders,which are risk factors for the progression of cirrhosis and have a serious negative impact on their prognosis.Therefore,it is essential to recognize and assess these conditions as early as possible and implement appropriate interventions.However,there are no standardized clinical criteria for the diagnosis of cirrhotic malnutrition and sarcopenia,which requires clinicians to integrate different assessment methods.This article examines the current research status,etiology,and diagnostic methods of cirrhotic malnutrition,sarcopenia,and abnormal lipid metabolism,offering a scientific foundation for further studies in these areas.
关键词
肝硬化/营养不良/肌肉减少症/脂质代谢异常Key words
Liver Cirrhosis/Malnutrition/Sarcopenia/Abnormal Lipid Metabolism引用本文复制引用
出版年
2024
NETL
NSTL
万方数据