Application of pulmonary ultrasound combined with umbilical artery blood gas analysis in evaluating the severity of disease for preterm infants with NRDS
Objective:To investigate pulmonary ultrasound combined with umbilical artery blood gas analy-sis in evaluating the severity of premature infants with respiratory distress syndrome(NRDS).Methods:From May 2020 to May 2022,82 cases of NRDS of premature infants admitted to The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture who underwent X-ray,pulmonary ultrasound and umbilical artery blood gas analysis were selected as the study subjects.According to chest radiographs,the infants were divided into the mild group(Grade Ⅰ-Ⅱ,n=52)and severe group(Grade Ⅲ-Ⅳ,n=30).All the children were examined by pulmonary ultrasound,and their pul-monary ultrasound score was calculated,and the umbilical artery blood gas analysis indicators such as pH value,partial pressure of oxygen(PO2),partial pressure of carbon dioxide(PCO2),and alkali sur-plus(BE),were measured.The factors of the severity of NRDS in premature infants were analyzed by single factor and logistic regression,and the diagnostic value of pulmonary ultrasound combined with umbilical artery blood gas analysis index for the condition of children was determined by the re-ceiver operator characteristic(ROC)curve.Results:There was no significant difference in sex,gesta-tional age and birth weight between the two groups(P>0.05).There were significant differences in maternal delivery mode,neonatal asphyxia,pregnancy complications,premature rupture of mem-branes,and intrauterine bacterial infection between the two groups(P<0.05);the lung ultrasound score in the mild group was(28.64±5.33),which was significantly higher than that in the control group(23.45±4.16)(P<0.05);pH value,PO2,and BE in the severe group were significantly lower(P<0.05),and PCO2 was significantly higher than that respectively in the mild group(P<0.05);lo-gistic regression analysis showed that neonatal asphyxia,premature rupture of membranes,intrauter-ine bacterial infection,lung ultrasound score,pH,PO2,PCO2,and BE were risk factors for the severity of NRDS in premature infants(P<0.05);ROC curve showed that the combined diagnostic value of pulmonary ultrasound and umbilical artery blood gas analysis was better than that of single di-agnosis(P<0.05).Conclusion:Pulmonary ultrasound score and umbilical artery blood gas analysis indicators have a certain value in evaluating the severity of NRDS in premature infants,and their com-bined diagnostic value is the highest.
Pulmonary UltrasoundUmbilical Artery Blood Gas Analysis IndicatorsPrema-ture InfantRespiratory Distress SyndromeSeverity of Disease
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维普
