Objective:To retrospectively analyze cervical screening data from 11 826 women of appropriate age in Wuchang in 2022,to determine the prevalence of human papillomavirus(HPV)in the popula-tion of Wuchang District,Wuhan,China,and to further analyze the possible relationship between HPV and cervical lesions.Methods:A total of 11 826 women aged 30-65 years in Wuchang District,Wuhan City from January 1,2022,to August 7,2022,were selected for HPV detection by artificial intelligence cytological examination(TCT)and cervical cancer screening.SPSS 27.0 was used to ana-lyze the detection rate of HPV infection subtypes,the distribution of HPV subtypes at different ages,and the relationship between HPV subtypes and the degree of cervical intraepithelial lesions.Results:The HPV infection rate was 10.37%(1 226/11 826).Among the 15 HPV subtypes,the top three with the highest infection rate were HPV52(3.26%),HPV58(1.46%),and HPV16(1.21%).The age group with the highest HPV detection rate was the 55-59-year-old group,followed by the 30-34-year-old group,and the top three subtypes with the highest infection detection rate were HPV52,HPV58,and HPV16.According to the screening process,a total of 487 women underwent colposco-py and cervical pathology examinations,and 59 of them were diagnosed with cervical cancer and pre-cancerous lesions.The top three HPV subtypes with the highest infection rate were HPV16(45.76%),HPV52(23.73%),and HPV58(15.25%),respectively.In the patients with cervical can-cer and precancerous lesions,the incidence of multiple HPV infections was 7.75%(10/129),which was 1.73 times higher than the incidence of single HPV infections at 4.47%(49/1 097).Conclusion:The HPV infection rate in Wuchang District was 10.37%,the top three subtypes with the highest in-fection detection rate were HPV52,HPV58,and HPV16.The age group with the highest HPV de-tection rate was 55-59 years old,followed by 30-34 years old,and the top three subtypes were HPV52,HPV58,and HPV16.The detection rates of HPV52,HPV58,and HPV16 were also the highest in patients with high-grade cervical intraepithelial lesions,which was slightly different from the HPV18 subtype reported abroad as the most common carcinogenic subtype.In patients with cervical cancer and precancerous lesions,the incidence of multiple HPV infections was 1.73 times of that of single HPV infection.
Human PapillomavirusGene SubtypeCervical CancerPrecancerous Lesions
万方数据
