首页|强脉冲光联合超分子水杨酸在玫瑰痤疮治疗中的疗效

强脉冲光联合超分子水杨酸在玫瑰痤疮治疗中的疗效

Efficacy and safety evaluation of intense pulsed light therapy combined with salicylic acid in rosacea treatment

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目的:分析强脉冲光联合超分子水杨酸治疗玫瑰痤疮的有效性及安全性.方法:研究对象为 2023年4月—10月于武汉大学中南医院就诊的玫瑰痤疮患者(共40例),并将其随机分为对照组及研究组(各20例).对照组患者进行强脉冲光治疗,研究组患者进行强脉冲光联合超分子水杨酸治疗,治疗时间为12周.通过云镜皮肤分析检测仪和患者自评检测比较治疗前后对照组及研究组患者的总有效率、面部红斑量、皮损的减少率及不良反应发生率.结果:治疗12周后,研究组的总有效率显著高于对照组(P<0.05);与治疗前相比,治疗后两组的面部红斑量,明显降低,且研究组低于对照组(P<0.05).治疗后,研究组与对照组不良反应发生率的比较,差异无统计学意义(P>0.05).结论:强脉冲光联合超分子水杨酸治疗玫瑰痤疮,临床效果显著,可显著减少皮损及面部红斑量,且安全性好.
Objective:To explore the efficacy and safety of intense pulsed light(IPL)therapy combined with supramolecular salicylic acid in rosacea treatment.Methods:A total of 40 patients with rosacea admit-ted to Zhongnan Hospital of Wuhan University from April to October 2023 were enrolled as the study subjects,and were randomly divided into the study group(n=20),with IPL therapy combined with supramolecular salicylic acid treatment,and the control group(n=20),with IPL therapy alone.After 12 weeks of treatment,the total effective rate,facial erythema score,and the incidence of adverse re-actions during treatment were evaluated in both groups.Results:The total effective rate of the control group was lower than that of the study group after 12 weeks of treatment(P<0.05).After treatment,the facial erythema score in both groups decreased,and the study group showed lower values than the control group(P<0.05).There was no significant difference in the incidence of adverse reactions be-tween the two groups(P<0.05).Conclusion:IPL-combined salicylic acid treatment of rosacea demonstrates superior clinical efficacy and a good safety profile.It can effectively promote the recovery of skin lesions,and reduce facial erythema.

RosaceaIntense Pulsed Light TherapySalicylic Acid

蓝世齐、梁嫔、唐宇、宋继权、刘琴

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武汉大学中南医院皮肤科 湖北 武汉 430071

玫瑰痤疮 强脉冲光 超分子水杨酸

2024

武汉大学学报(医学版)
武汉大学

武汉大学学报(医学版)

CSTPCD
影响因子:0.959
ISSN:1671-8852
年,卷(期):2024.45(12)