Efficacy comparison between soluble reconstruction barrier microneedle and Nd:YAG Q-switching 1 064 nm laser in the treatment of melasma
Objective:To compare the clinical efficacy of soluble reconstruction barrier microneedles and Nd:YAG Q-switching 1064 nm laser in melasma treatment.Methods:Ninety subjects with melasma were included and were randomly divided into three groups using a random number table according to their treatment as Group 1:the combination of tranexamic acid and soluble reconstructive barrier mi-croneedle group,Group 2:the soluble reconstructive barrier microneedle group,and Group 3:the la-ser combined with tranexamic acid smear group.All the patients were treated once a week for a total of 6 times.This study used a skin analysis system to evaluate the condition of melasma skin.Results:After treatment,the skin conditions of all three groups were improved.The therapeutic effect of the combination of tranexamic acid and soluble reconstruction barrier microneedle group showed no signifi-cant difference from that of the soluble reconstruction barrier microneedle group,and the efficacy of both groups(Group 1 and Group 2)was significantly better than that of laser combined tranexamic acid smear group.Conclusion:Soluble reconstruction barrier microneedle therapy has a good therapeutic effect on damaged skin and can significantly reduce the loss of damaged skin in patients.Especially in pain management,soluble reconstruction barrier microneedles have shown greater advantages than tra-ditional laser therapy.
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