可溶性重建屏障微针联合氨甲环酸与调Q 1 064 nm激光治疗黄褐斑的疗效比较
Efficacy comparison between soluble reconstruction barrier microneedle and Nd:YAG Q-switching 1 064 nm laser in the treatment of melasma
黄彦华 1赵梦洁 1谢君1
作者信息
- 1. 武汉大学中南医院皮肤科 湖北 武汉 430071
- 折叠
摘要
目的:比较可溶性重建屏障微针与调Q1 064 nm激光治疗黄褐斑的疗效与安全性.方法:招募黄褐斑受试者90例,随机分成三组:可溶性重建屏障微针联合氨甲环酸涂抹组、可溶性重建屏障微针组,每周治疗1次,调Q1 064 nm激光联合氨甲环酸涂抹组,每周治疗1次,均行6次治疗.治疗前后采用皮肤分析系统来评价黄褐斑皮肤改善情况并进行统计学分析.结果:经治疗后,三组患者皮肤分析系统评分均降低,肉眼观黄褐斑皮肤情况均有不同程度改善.其中,可溶性重建屏障微针联合氨甲环酸涂抹组疗效与可溶性重建屏障微针组疗效改善均在90%以上,疗效显著优于调Q1 064 nm激光联合氨甲环酸涂抹组.结论:可溶性重建屏障微针治疗黄褐斑有良好疗效,较传统激光治疗具有快速起效和无痛特点.
Abstract
Objective:To compare the clinical efficacy of soluble reconstruction barrier microneedles and Nd:YAG Q-switching 1064 nm laser in melasma treatment.Methods:Ninety subjects with melasma were included and were randomly divided into three groups using a random number table according to their treatment as Group 1:the combination of tranexamic acid and soluble reconstructive barrier mi-croneedle group,Group 2:the soluble reconstructive barrier microneedle group,and Group 3:the la-ser combined with tranexamic acid smear group.All the patients were treated once a week for a total of 6 times.This study used a skin analysis system to evaluate the condition of melasma skin.Results:After treatment,the skin conditions of all three groups were improved.The therapeutic effect of the combination of tranexamic acid and soluble reconstruction barrier microneedle group showed no signifi-cant difference from that of the soluble reconstruction barrier microneedle group,and the efficacy of both groups(Group 1 and Group 2)was significantly better than that of laser combined tranexamic acid smear group.Conclusion:Soluble reconstruction barrier microneedle therapy has a good therapeutic effect on damaged skin and can significantly reduce the loss of damaged skin in patients.Especially in pain management,soluble reconstruction barrier microneedles have shown greater advantages than tra-ditional laser therapy.
关键词
可溶性重建屏障微针/氨甲环酸/激光/黄褐斑Key words
Soluble Reconstructive Barrier Microneedles/Tranexamic Acid/Laser/Melasma引用本文复制引用
出版年
2024
NETL
NSTL
万方数据