Comparison of the efficacy of non-invasive hydrating and intense pulsed light in the treatment of rosacea erythema
Objective:To compare the efficacy of non-invasive hydrating treatment combined with topical application of tranexamic acid and botulinum toxin type A versus intense pulsed light therapy in the treatment of erythematous rosacea.Methods:Ninety patients with erythematous rosacea were recruited and randomly allocated into three groups.The control group 1 received intense pulsed light therapy combined with topical application of tranexamic acid,control group 2 was treated with tranexamic acid alone,and the experimental group underwent non-invasive hydrating treatment with botulinum toxin type A and tranexamic acid.The patients were assessed using the CBS® cloud mirror skin analyzer to determine facial redness area(mm2),redness concentration(％),and clinician's erythe-ma assessment(CEA)scale,before the treatment and on day 28 of follow-up.Results:There were significant differences in facial redness area and redness concentration between the pretreatment and post-treatment periods across all the three groups(P<0.05),with the experimental group demonstrating superior efficacy compared to control group 1 and control group 2(P<0.001).Conclusion:Non-invasive hydrating treatment exhibits a more favorable therapeutic outcome than in-tense pulsed light for the management of erythematous rosacea.
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