湖南城市学院学报(自然科学版)2025,Vol.34Issue(1) :74-78.DOI:10.3969/j.issn.1672-7304.2025.01.0011

樟脑环糊精包合物的制备研究

Study on preparation of camphor cyclodextrin inclusion complex

彭天英 林一婷 刘赛文 殷志红
湖南城市学院学报(自然科学版)2025,Vol.34Issue(1) :74-78.DOI:10.3969/j.issn.1672-7304.2025.01.0011

樟脑环糊精包合物的制备研究

Study on preparation of camphor cyclodextrin inclusion complex

彭天英 1林一婷 1刘赛文 1殷志红1
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作者信息

  • 1. 湖南城市学院 材料与化学工程学院,湖南 益阳 413000
  • 折叠

摘要

环糊精因其独特的空间结构与化学性质受到研究者的广泛关注.环糊精通过自组装作用可以与多种客体进行包合从而形成包合物,且包合物的稳定性一般取决于氢键、范德华力及配位作用.樟脑在医疗和生活中都是重要的材料,具有清凉、止痛、驱蚊杀虫的功效.用环糊精包合樟脑,可以起到缓释作用,提高樟脑的热稳定性,从而扩大其在各个领域的适用范围.本研究使用樟脑和环糊精作为原料,通过饱和水溶液法来制备樟脑环糊精包合物,考察了不同条件下樟脑和环糊精包合物的制备情况,并通过红外、差式扫描量热仪对包合物进行了分析.研究结果表明,γ-环糊精对樟脑进行包合,条件温和,产率较高,提高了樟脑的热稳定性.

Abstract

Cyclodextrin has attracted extensive attention because of its unique spatial structure and chemical properties.Cyclodextrins can be incorporated with a variety of objects through self-assembly to form inclusion complexes,and the stability of the inclusion complexes generally depends on hydrogen bonds,van der Waals forces and coordination.Camphor is an important material in medical treatment and daily life.It has the functions of cooling,relieving pain,and repelling mosquitoes and insects.The inclusion of camphor with cyclodextrin can play a slow-release role and improve the thermal stability of camphor,thereby expanding its scope of application in various fields.In this study,camphor and cyclodextrin are used as raw materials to prepare camphor cyclodextrin inclusion complexes by saturated aqueous solution method.The preparation of camphor and cyclodextrin inclusion complexes under different conditions is investigated,and the inclusion complexes are analyzed by infrared and differential scanning calorimetry.The results show that the inclusion of camphor with γ-cyclodextrin has mild conditions and high yield,which improves the thermal stability of camphor.

关键词

樟脑/环糊精/包合物/制备

Key words

camphor/cyclodextrin/inclusion complex/preparation

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出版年

2025
湖南城市学院学报(自然科学版)
湖南城市学院

湖南城市学院学报(自然科学版)

影响因子:0.304
ISSN:1672-7304
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