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金芪降糖片组方中总黄酮提取工艺研究

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本文采用乙醇回流提取法对金芪降糖片组方的总黄酮进行提取,将总黄酮提取量作为指标,通过单因素实验结果选取对金芪降糖片组方中总黄酮提取量影响较大的 3 个因素进行正交实验.得出最佳提取方案:乙醇体积分数为 75%、料液比为 1∶20(g∶mL)、浸泡时间为 1.75h、提取时间为 1.5h、提取温度为 65℃,此时总黄酮提取量为 8.303mg·g-1.
Study on the extraction technology of total flavonoids from Jinqi Jiangtang Tablets presciption
In this paper,ethanol reflux extraction method was used to extract total flavonoids from Jinqi Jiangtang tablet formula,and the total flavonoids extraction amount was taken as an index.Three factors that had a greater influence on the total flavonoids extraction amount of Jinqi Jiangtang tablet formula were selected through the results of single factor experiment,and orthogonal experiments were conducted.The optimal extraction scheme was as follows:the ethanol volume fraction of 25%,solid-liquid ratio of 1∶20,soaking time of 1.75h,extraction time of 1.5h and extraction temperature of 65℃,the total extraction amount of flavonoids was 8.303mg·g-1.

total flavonoidsJinqi Jiangtang tabletsethanol reflux extractionextraction optimizatio

董方昕、姚瑶、毛浩洋、吴毓斌、李思明

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哈尔滨商业大学 药学院 细胞与分子生物学研究所,黑龙江 哈尔滨 150076

总黄酮 金芪降糖组方 乙醇回流提取法 提取工艺优化

黑龙江省自然科学基金优秀青年基金黑龙江省重点研发计划指导类项目哈尔滨商业大学创新人才支持计划

YQ2021H002GZ20210110

2024

化学工程师
黑龙江省化工研究院

化学工程师

CSTPCD
影响因子:0.243
ISSN:1002-1124
年,卷(期):2024.38(3)
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