OBJECTIVE To establish a UPLC method for the simultaneous determination of nine active components in Rendongteng Capsules.METHODS Shim-pack GIST C18 colum,mobile phase of acetonitrile:0.04％phosphoric acid gradient elution;flow rate of 0.4mL·min-1,detection wavelength of 327nm and 240nm,column temperature of 25℃,injection volume of 10μL.RESULTS The linear relationship,precision and stability of the nine active components were all in line with the requirements of methodology,the average recovery rate was 101.3％～102.6％.CONCLUSION The method is simple,accurate and feasible,which can provide the basis for the quality control of Rendongteng Capsules.
维普
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