Phase transfer catalytic synthesis of 2,4-dichlorophenoxyacetic acid
2 ,4-Dichlorophenoxy acetic acid is synthesized by etherification of chloroacetic acid and 2,4-dichlorophenol with phase transfer catalyst which selected from tetrabutylammonium bromide (TBAB), tetraethylammonium bromide (TEAB) and polyethylene gtycol-600 (PEG-600) by potassium carbonate. The effect of different catalysts on yield of 2,4-dichlorophenoxy acetic acid is studied. As a result, the optimal conditions are obtained as following: using PEG-600/KI as the most suitable catalyst, the molar ratio of 2,4-dichlorophenol, chloroacetic acid, PEG-600 and KI is 1 ∶ 2 ∶ 0. 06 ∶ 0. 1. Under these conditions, the yield of 2,4-dichlorophenoxy acetic acid reaches 94. 2%.
2,4-Dichlorophenoxy acetic acidPhase transfer catalysis (PTC)Chloroacetic acid2,4-dichlorophenol
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维普
