With the rapid development of social economy and the continuous improvement of people's living standards,medical and health care have taken on an important strategic position.As an important analytical detection method,biosensing technology plays a key role in the field of medical health.Piezoelectric biosensor,as a new kind of biosensor,utilizes piezoelectric materials for biological analysis.Piezoelectric biosensor has the advantages of good stability,fast detection speed,high accuracy and simple operation,and has important application value in biomedicine,health monitoring and disease prevention and control.Herein,we review the research progress of piezoelectric biosensor home and abroad in recent years,and introduce the principle of piezoelectric biosensors based on the piezoelectric effect of quartz crystal microbalance and the commonly used piezoelectric materials,including inorganic piezoelectric materials,organic piezoelectric materials,piezoelectric composite materials and biological piezoelectric materials.In addition,the applications of piezoelectric biosensors in human health monitoring and disease prevention and control are also introduced,such as the monitoring of physiological signs,such as heart rate,blood pressure and pulse,the detection of biomarkers and epidemic viruses such as SARS-CoV-2(COVID-19).Finally,the current problems faced by piezoelectric biosensors are summarized,and the future development of piezoelectric biosensors is prospected.
关键词
生物传感/压电材料/生物标志物/疾病防控/压电效应
Key words
biosensor/piezoelectric materials/biomarkers/disease prevention and control/piezoelectric effect