摘要
水凝胶因其优异柔软性、湿润性、响应性和生物相容性等特性已成为跨学科研究最广泛的材料之一.但水凝胶的力学性能较差,无法满足作为一些特殊材料的使用.纳米纤维因其高长径比、纤维形貌均匀和易功能化等特点,被用来制备具有纳米尺寸、多孔结构和可调机械性能的纳米纤维复合水凝胶.纳米纤维复合水凝胶具有合适的机械性能、延展性、黏附性和可以模拟细胞外基质(ECM)的微观结构及细胞的微环境等特点,使其在多领域广泛应用.本文从纳米纤维复合水凝胶的分类、制备方法及其在多功能伤口敷料、组织工程、传感器、吸滤材料等领域的开发及应用进行总结,并对其未来的发展进行了展望.
Abstract
Hydrogels have become one of the most widely researched materials across disciplines due to their excellent softness,wettability,responsiveness and biocompatibility.However,the mechanical properties of hydrogels are poor and cannot meet the use of some special materials.Nanofibers have been used to prepare nanofiber composite hydrogels with nano-size,porous structure and tunable mechanical properties due to their high aspect ratio,uniform fiber morphology and easy functionalization.Nanofiber composite hydrogels have suitable mechanical properties,ductility,adhesion,and the ability to mimic the microstructure of the extracellular matrix(ECM)and the microenvironment of the cell,which makes them widely used in many fields.This paper summarizes the classification of nanofiber composite hydrogels,their preparation methods and their development and application in the fields of multifunctional wound dressings,tissue engineering,sensors,and filter absorption materials future development.
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