Recognition of Chiral Tryptophan using Electrochemical Sensors Constructed with Chiral Metal-Organic Frameworks
Chiral metal organic framework L-Glu-Phen-Cu(Ⅱ)was synthesized by one pot method using Cu(Ⅱ),1,10-phenanthroline(Phen),and L-glutamic acid(L-Glu)as raw materials.L-Glu-Phen-Cu(Ⅱ),as a novel electrochemical sensing interface,has good enantiomeric selectivity(IL/ID=2.24)and is used for chiral recognition of tryptophan(Trp)enantiomers.Cu(Ⅱ)and L-Glu coordination constructed the stereoselectivity of L-Glu-Phen-Cu(Ⅱ),while Cu(Ⅱ)and Phen coordination enhanced the electrochemical signal.This study not only provides a readily adjustable and low-cost sensing interface for efficient Trp enantiomer detection,but also provides a feasible new idea for using directly synthesized chiral MOFs for chiral identification.
NETL
NSTL
万方数据
维普
