As a traditional Chinese medicine,the Agrimoniae Herba has the functions of astringent,detoxification and tonifying kidney.The Agrimonolides are the main isocoumarins in it.They have been widely concerned because of their various pharmacological activities.However,because of their low content,the artificial synthesis of these compounds is particularly important.In this paper,a concise synthetic method of(±)-Agrimonolide has been explored,which provided a methodology for the asymmetric synthesis of this kind of compounds.
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