Research Progress in Squaraine Dyes for Application to Bioassay and Biotherapy
Squaraine dyes have specific structural and physicochemical properties,such as strong absorption in the visible to near-infrared region,unique fluorescence properties and excellent photostability.They have been widely used in many fields such as biological imaging,photosensitizer and solar energy conversion.It is increasingly necessary to develop squaraine dyes with high extinction coefficient and maximum absorption wavelength.In this paper,the structural characteristics,photophysical properties and photostability of squaraine were introduced,and the applications of squaraine dyes in bioimaging,photodynamic therapy,photothermal therapy and multimodal collaborative therapy in the past 10 years were reviewed according to the research direction of squaraine in biomedicine,so as to provide reference for further development of squaraine dyes.
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