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响应面法研究压片工艺对产气药密度的影响

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以现有批产配方产气药药片压制过程的成型特性为研究对象,分别研究了压片机工作压力、模具直径和压片机转速等对产气药密度的影响,运用响应面法建立了 3个变量与产气药密度之间的关系,并建立了数学回归方程,得出了 3个变量对产气药密度影响的显著性顺序.
Effect of tablet pressing process on density of gas generating agent studied by response surface method
Taking the molding characteristics of gas generating agent tablets of existing batch production formulations during the press process as the research object,the effects of the working pressure of the tablet press,the diameter of the mould and the rotating speed of the tablet press,etc.on the density of gas generating agent were investigated respectively.The relationship between the three variables and the density of gas generating agent was established by using the response surface method,and the mathematical regression equation was also established.The significance order for the effects of the three variables on the density of gas generating agent was obtained.

gas generating agentresponse surface methodregression equationdensity

杜涛、罗运强、左童久、郭帅、郭锋杰、张俊、任响宁

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湖北航鹏化学动力科技有限责任公司,湖北襄阳 441048

产气药 响应面法 回归方程 密度

2024

化学推进剂与高分子材料
黎明化工研究院有限责任公司

化学推进剂与高分子材料

影响因子:0.289
ISSN:1672-2191
年,卷(期):2024.22(5)