Synthesis, Structure and Biological Activities of 3-Substituted Phenoxymethyl-4-amino-1,2,4-triazol-5-thione Schiff Bases
Five 4-amino-4,5-dihydro-3-(substituted phenoxymethyl)-1,2,4-triazole-5-thione Schiff bases were synthesized by 4-amino-4,5-dihydro-3-(substituted phenoxymethyl)-1,2,4-triazole-5-thione and 4-fluorobenzaldehyde with acetic acid as a catalyst and solvent. The chemical structures of the compounds have been confirmed by 1H NMR, IR and elemental analysis. Their biological activities were investigated and the results showed that all of the compounds exhibited excellent fungicidal activities.
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