甘麦大枣汤联合失眠认知行为疗法治疗抑郁共病失眠的疗效观察
Observation on Therapeutic Effect of Ganmai Dazao Decoction Combined with Cognitive Behavioral Therapy for Insomnia on Insomnia Comorbid with Depression
杨淑珍 1高胜奎 2白东梅 1郭军雄 1黄蜜 1蔡建成1
作者信息
- 1. 河西学院
- 2. 甘肃省张掖市红十字精神病院,甘肃 张掖 734000
- 折叠
摘要
目的:探讨甘麦大枣汤联合失眠认知行为疗法(CBT-I)治疗抑郁共病失眠的疗效,为抑郁共病失眠的临床治疗提供新方法.方法:选取某精神卫生中心收治的110例抑郁共病失眠患者,随机分为观察组和对照组各55例,对照组给予常规西医治疗,观察组给予为期6周的甘麦大枣汤联合CBT-I治疗,比较两组患者HAMD-17、PSQI和SERS评分差异.结果:观察组干预结束时和随访时PSQI、SERS得分低于对照组(P＜0.01),PSQI得分、HAMD得分、SERS得分均低于干预前(P＜0.01);对照组干预结束时PSQI总分、HAMD总分均下降(P＜0.01或P＜0.05),SERS得分上升(P＜0.01).结论:甘麦大枣汤联合CBT-I对抑郁共病失眠的临床效果显著,可持续缓解抑郁症状,提升睡眠质量,且安全性高,在临床中具有推广价值.
Abstract
Objective:To investigate the therapeutic efficacy of Ganmai Dazao Decoction in conjunction with Cognitive Behav-ioral Therapy for Insomnia(CBT-I)in the treatment of insomnia coexisting with depression,aiming to provide a novel clinical inter-vention for the condition.Methods:A total of 110 patients with comorbid depression and insomnia,admitted to a mental health cen-ter,were randomly allocated into either an observation group or a control group,with 55 cases in each.The control group received standard Western medication,whereas the observation group was administered Ganmai Dazao Decoction in combination with CBT-I for a duration of 6 weeks.The differences in Hamilton Depression Rating Scale-17(HAMD-17),Pittsburgh Sleep Quality Index(PSQI),and Self-Rating Depression Scale(SERS)scores between the two groups were analyzed.Results:The observation group exhibited significantly lower PSQI and SERS scores compared to the control group(P<0.01).Additionally,the PSQI score,HAMD score,and SERS score in the observation group were all reduced following the intervention when compared to baseline(P<0.01).At the conclusion of the intervention,the control group showed a decrease in the total PSQI and HAMD scores(P<0.01 or P<0.05),and an increase in the SERS score(P<0.01).Conclusion:Ganmai Dazao Decoction,in synergy with CBT-I,demonstrates a notable clinical effect on insomnia complicated by depression,providing sustained relief from depressive symptoms and enhancement of sleep quality,with high safety profiles.This regimen merits broader application in clinical settings.
关键词
甘麦大枣汤/失眠认知行为疗法/抑郁/失眠Key words
Ganmai Dazao Decoction/Cognitive Behavioral Therapy for Insomnia/Depression/Insomnia/Secondary Reaction引用本文复制引用
出版年
2024
NETL
NSTL
万方数据