Exploring the Current Status and Trend of Allicin Application in Medicine Based on CNKI-CiteSpace
Objective:To visualize and analyze the current research status,hotspots,and trends of allicin in the med-ical field,and to provide a reference for subsequent related research.Methods:This study systematically searched the Chi-na Knowledge Network database for allicin-related medical research literature and employed bibliometric methods based on CiteSpace 6.1.R6 software to visualize and analyze the number of publications,journals,authors,keywords,and other aspects.Results:A total of 333 valid literature were included,with the number of publications varying annually.The Chi-nese Journal of Integrated Medicine and Western Medicine was the journal with the highest number of publications,and Professor Zaixiang Shi's team conducted extensive research on the use of allicin in combination with Western medicine for cardiovascular diseases.Keyword co-occurrence and clustering analysis revealed that medical research on allicin primari-ly focuses on two aspects:chronic disease control and antibacterial properties.Allicin has been shown to effectively inhibit tumor cell invasion,metastasis,and promote apoptosis.Current research hotspots for allicin center around the study of its anti-inflammatory,antioxidant,and anticancer mechanisms.Conclusion:Research on allicin in the medical field is ac-tively evolving,and there is a need for enhanced collaboration and communication among various research teams.The evi-dence for the anti-inflammatory,antioxidant,anticancer,and antibacterial activities of allicin is substantial,and as its mechanism of action becomes clearer,the clinical application of allicin holds great promise.
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