Advances in biosensing applications of electrochemiluminescence carbon dots
Electrochemiluminescence(ECL),with the advantages of controllability,low background signal,and high sensitivity,provides a powerful technique for the trace sensing of biomarkers.However,traditional ECL emitters usually suffer from poor biocompatibility,high price and difficulty in preparation.Carbon Dots(CDs),with the merits of excellent biocompatibility,inexpensive of raw material,and easy-to-prepare,have attracted wide interest in electrochemiluminescent biosensors.In this paper,we summarize the synthesis methods of carbon dots,surface doping/modification of carbon dots,and further discuss their applications of carbon dots as luminophore,coreactant,coreaction accelerator and quencher in developing of biosensing.More importantly,the applications of carbon dots in bacterial detection,nucleic acid detection,protein detection,and cell detection were reviewed,which provides a promising reference for the research of carbon dots in biological detection.
万方数据
维普
