Application analysis of preoperative pretreatment with pentylenethyclidine hydrochloride in laparoscopic total hysterectomy
Objective To observe the effectiveness and safety of preoperative pretreatment with pentylenethyclidine hydrochloride in laparoscopic total hysterectomy.Methods 125 patients who underwent total hysterectomy were selected and divided into two groups by random number table method.The routine group consisted of 62 patients who were received preoperative atropine pretreatment as an auxiliary anesthesia,while the experimental group consisted of 63 patients who were received preoperative pentylenethyclidine hydrochloride pretreatment as an auxiliary anesthesia.The anesthesia effects and safety of the two groups of patients were compared.Results Before surgery,there was no statistically significant difference in the basic values of HR,MAP,and gastrointestinal motility hormone indicators between the two groups of patients(P>0.05).During surgery,the maximum and minimum values of HR and MAP,as well as the additional and total dosage of anticholinergic drugs in the experimental group were lower than normal in the conventional group(P<0.05).After surgery,the incidence of GAS,MLT,and adverse anesthesia reactions in the experimental group were lower than those in the conventional group(P<0.05).Conclusion Preoperative use of pentylenethyclidine hydrochloride as an adjuvant anesthesia can maintain the stability of basic physical signs in patients undergoing total hysterectomy during the perioperative period.Compared with conventional anticholinergic drugs,the total dosage of pentylenethyclidine hydrochloride is lower,which can effectively avoid excessive activation of gastrointestinal motility and reduce the risk of anesthesia related adverse reactions.
total hysterectomypentylenethyclidine hydrochloridegeneral anesthesiabasic physical signs
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