Objective To analyze the risk factors for ovarian hyperstimulation syndrome(OHSS)in assisted reproductive technology(ART)and observe the effectiveness of acupuncture intervention.Methods 123 infertile patients who underwent ART treatment were selected,70 cases without OHSS were included in the control group,and 53 cases with OHSS were included in the combined group.The risk factors of ART were analyzed,and the effect of acupuncture intervention was observed.Results Age,BMI,FSH,LH,AMH,trigger day E2,AFC,initial dose of Gn,total dose of Gn,and Gn days were independent factors affecting the occurrence of OHSS in ART treatment for infertile patients.Age<28 years old,BMI<20 kg/m2,LH baseline value≥5 mIU/mL,AMH≥4 ng/mL,AFC≥20,Gn initial dosage>200 IU,Gn total dosage>3 000 IU,Gn time>10 d,trigger day E2level>4 000 pg/mL are risk factors for OHSS during ART in infertile patients.After acupuncture intervention,the LH,AMH and whole embryo freezing rate of OHSS patients were lower than that before intervention,and the number of eggs obtained was higher than that before intervention(P<0.05).Conclusion Young age,low BMI index,high LH and AMH levels,high AFC,high Gn dosage,long duration,and high E2 levels on trigger day are risk factors for OHSS during ART.Acupuncture intervention can reduce sexual hormone levels and OHSS whole embryo cryopreservation rate in patients with OHSS,and increase the number of retrieved eggs.